Quantitative Estimation of Andrographolide by Reverse Phase-High Liquid Chromatography Method from Andrographis Paniculata Nees.

Simultaneous determination of four andrographolides in Andrographis paniculata Nees by silver ion reversed-phase high-performance liquid chromatography.

A rapid and sensitive silver ion high-performance liquid chromatographic (Ag[I]-HPLC) method is developed for the simultaneous determination of the biologically active diterpenoids andrographolide, 14-deoxy-11,12-didehydroandrographolide, 14-deoxyandrographolide, and neoandrographolide in Andrographis paniculata Nees. HPLC is carried out for determining andrographolide and its derivatives with ...

Andrographolide isolated from Andrographis paniculata Ness

Andrographolide isolated from Andrographis paniculata Ness (A and 1.40 mM induced DNA fragmentation and increased the percentage o breast cancer cell line was treated for 24 , 48 and 72 h. The results de induce apoptosis in TD-47 human breast cancer cell line in a time and increase expression of p53, bax , caspase-3 and decrease ex immunohistochemical analysis.

Therapeutic Potential of Andrographolide Isolated from the Leaves of Andrographis paniculata Nees for Treating Lung Adenocarcinomas

Andrographolide is one of the major diterpene lactones found in Andrographis paniculata Nees and exhibits remarkable inhibitory effects on various cancers. In this study, the antipulmonary cancer effects of andrographolide were studied in a lung tumor mouse model induced by human vascular endothelial growth factor A 165 (hVEGF-A165). These results demonstrated that andrographolide significantly...

Assessment report on Andrographis paniculata Nees, folium

Is Andrographis paniculata extract and andrographolide anaphylactic?

Andrographis paniculata, "King of bitters" is a popularly known medicinal plant extensively used in many parts of the world for treatment of various diseases. Since recent past, anaphylactic/allergic type adverse events were reported upon A. paniculata usage, the study aimed to evaluate the anaphylactic and anaphylactoid potential of A. paniculata extract and andrographolide (a major phytoactiv...